The Weekly Roundup: Cannabidiol Compounds (4.27.18)

April 27, 2018 | Pamela Youngberg Dickson

The times they are a-changin'. Compounds found in cannabis are rapidly gaining appreciation from the mainstream medical community. Last week, the FDA announced its support of a cannabidiol compound for its potential to treat seizure disorders. The treatment would be marketed under the name Epidiolex by UK-based GW Pharmaceuticals and, according to CEO Justin Gover, the approval of the drug “will mark a sea change in the acceptability of cannabinoids as therapy.” The deadline for approval is at the end of June, but many are speculating the unanimous support from the advisory panel indicates a slam-dunk for the drug maker.

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The Weekly Roundup: Adherence (4.20.18)

April 20, 2018 | Pamela Youngberg Dickson

A team of researchers from the University of South Florida may have found a solution to an adherence problem among statin patients who are experiencing muscle pain. They published the results of their intervention in Diabetes, Obesity and Metabolism and determined that using metformin in conjunction with a statin reduced muscle pain by 20-30 percent. Statin adherence is remarkably low—particularly after the first year and among women—given how effective they are in reducing LDL and decreasing cardiovascular risk.

Is adherence to statins different than to other medications?

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The Weekly Roundup: Melanoma (4.13.18)

April 13, 2018 | Pamela Youngberg Dickson

It’s the time of year when many of us spend a lot more time outside, moving our exercise regimens into the open air, holding BBQs, and shaking off winter’s deficit of vitamin D. It’s also the time of year to remind ourselves and patients about the importance of sun protection to reduce the risk of cancer. Melanoma has been particularly challenging for cancer researchers, particularly those in the immunotherapy field. While its study has gained momentum over the past ten years, immunotherapy has had a patchy history of effectiveness and adoption. (Here’s more on the interesting history of the concept circa the 1900s.) Scientists continue to hone in on what makes immunotherapy work—and not work—in cancer treatment. Of late, it’s thought that combinations of therapies may be the ticket, and this recent study has promise. Still, an ounce of prevention, right?: The CDC and the American Academy of Dermatology have a range of resources available, and we’ve put together this patient-facing download you can print or forward to your patients to remind them of the importance of sun safety.

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Smart-Fill at the Capitol

April 11, 2018 | Pamela Youngberg Dickson

Pharmacists from across the nation will converge in Washington D.C. on April 11 and 12 for the annual NCPA Congressional Pharmacy Summit. It’s a great opportunity to be an advocate for both independent pharmacy and for your patients.

We know the challenges of a prescription delivery market that is so heavily controlled by the PBMs. They determine which pharmacies are included in prescription benefit plans, how much they will be paid, and which drugs will be included in formularies. For independent pharmacies, PBMs are a particular threat: often, they try to persuade insurers to push patients to mail-order pharmacies or to pharmacies owned by the PBM itself—which would seem to be a clear (and actionable) conflict of interest in any other business. Limited networks, typically favoring chains, put patients in rural areas at a disadvantage, sometimes forcing them to drive many miles to access an in-network pharmacy.

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The Weekly Roundup: Advocacy (3.30.18)

March 30, 2018 | Pamela Youngberg Dickson

Two pharmacists from Smart-Fill sister companies Sterling Drug and Sterling Specialty Pharmacy testified last week before the Minnesota House on bills that would increase price transparency for pharmacy patients. Both bills seek to prevent patients from having to pay more than the “lowest allowable cost”: the least of the copay, the allowable claim amount, or the cash price—and not prevent pharmacists from informing their patients of the price differential. Similar legislation is being brought in other states as pharmacists wait for action at the federal level.

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The Weekly Roundup: Insomnia (3.9.18)

March 09, 2018 | Pamela Youngberg Dickson

A sleep doctor from Virginia Mason Medical Center recently penned a step-by-step guide to curing insomnia—drug-free. Brandon R. Peters, MD, a board-certified neurologist, recommends a combination of education and cognitive behavioral therapies over a six-week program he developed at Stanford, which now runs in the Seattle-based clinic. Sleep research may be particularly important for the elderly.

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The Weekly Roundup: Shingles Patch (3.2.18)

March 02, 2018 | Pamela Youngberg Dickson

This week, the FDA approved the super-sticky ZTlido, a non-opioid patch for nerve pain. The new product is expected to be a blockbuster at a time when a wide range of non-opioid treatments for chronic pain are highly sought. Sorrento Therapeutics’ ZTlido is expected to deliver relief to shingles patients more effectively than Lidoderm. Here’s a case for transdermal patches as a more effective drug delivery mechanism than oral ingestion—but they are not without their safety concerns

Here are a few other stories that might be of interest:

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