Colorectal cancer is the second leading cause of cancer deaths in the U.S.—and with appropriate screening, it doesn’t have to be. According to the CDC, regular screening can prevent 6 out of 10 colorectal cancer deaths. Both women and men are at risk for colorectal cancer, and that risk increases with age, so screening is recommended for adults over 50.

While screening is the best path to prevention, there are some risk factors that increase the likelihood of contracting the disease. The risk increases with age, but there are a few other factors that place people at high risk:

  • having an inflammatory bowel disease like Crohn’s, or ulcerative colitis;
  • inheriting genetic diseases such as familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer;
  • having polyps or a close relative with polyps or colorectal cancer.

For those with these higher risk factors, screening may be recommended earlier and more often. Although many people in the early stages of the disease don’t experience these, when symptoms do appear, they vary widely. Among them:

  • changes in your bowel habits (change in consistency);
  • blood in the stool;
  • weight loss;
  • abdominal discomfort like gas, cramps;
  • unexplained weakness or fatigue.

As always seems to be the case, there are some lifestyle choices a person can make to reduce their risk of getting colorectal cancer, as well as helping to improve outcomes.

  • Exercise. If you are not physically active, you're more likely to develop colon cancer.
  • Diabetes. People with diabetes and insulin resistance may have an increased risk of colon cancer.
  • Obesity. Being overweight increases the risk of colon cancer and of dying from the disease, and while obesity increases the risk for both genders, the link seems to be stronger in men.
  • Smoking. People who smoke are more likely than nonsmokers to die from colon cancer.
  • Alcohol. Heavy use of alcohol may increase your risk of colon cancer. Limited use (no more than 2 drinks a day for men, 1 for women) may have some health benefits, including a lower risk of colon cancer.
  • Radiation therapy for cancer. Radiation therapy directed at the abdomen to treat previous cancers may increase the risk of colon cancer.
  • Diet. Diets high in processed and red meats can raise your cancer risk. The current thinking is that supplemental fiber is not the panacea it was once thought to be, but a diet high in fiber from natural sources like vegetables, fruit, and whole grains has been linked to lower risk. Still, fiber plays an important role in managing or preventing other health issues—like diabetes and obesity—that impact colon health.